The exponential growth in maritime trade during the 21st century has posed notable challenges for container terminals, resulting in congestion and operational inefficiencies. This study delves into the efficacy of Amphibious Automated Guided Vehicles (AGVs) as an innovative remedy to tackle these issues and facilitate the shift towards autonomous operations at container terminals. Motivated by the need to optimize spatial utilization and reduce reliance on conventional material handling equipment in port areas, this study employs an agent-based modeling approach. Subse- quently, the formulated model is applied in a case study focusing on major Ports of the World. This study undertakes a critical examination of the potential of Amphibious AGVs in alleviating congestion and operational challenges faced by container terminals in the context of an increasingly interconnected global trade setting. By conducting a thorough examination of existing literature and creating a generalised simulation model, this study aims to offer valuable insights that can influence the evolution of container terminal operations.