The European Sentinel-3A satellite, launched by ESA in February 2016, followed by Sentinel-3B in April 2018, as a part of the Copernicus programme, is the second satellite to operate a SAR mode altimeter. SRAL is operated in SAR mode over the whole ocean and promises increased performance w.r.t. conventional altimetry. SCOOP (SAR Altimetry Coastal & Open Ocean Performance) is a project funded under the ESA SEOM (Scientific Exploitation of Operational Missions) Programme Element, to characterise the expected performance of Sentinel-3 SRAL SAR mode altimeter products, and then to develop and evaluate enhancements to the baseline processing scheme in terms of improvements to ocean measurements. Another objective is to develop and evaluate an improved Wet Troposphere correction for Sentinel-3. We present results from the SCOOP project that demonstrate the excellent performance of SRAL at the coast in terms of measurement precision, with noise in Sea Surface Height 20Hz measurements of less than 5cm to within 5km of the coast. We then report the development and testing of new processing approaches designed to improve performance close to the coast, including, for L1B to L2: Application of zero-padding Application of intra-burst Hamming windowing Exact beam forming in the azimuthal direction Restriction of stack processing to within a specified range of look angles. Along-track antenna compensation And for L1B to L2 Application of alternative re-trackers for SAR and RDSAR. Based on the results of this assessment, a second test data set was generated and we present an assessment of the performance of this second Test Data Set generated, and compare it to that of the original Test Data Set. Regarding the WTC for Sentinel-3A, the correction from the on-board MWR has been assessed by means of comparison with independent data sets such as the GPM Microwave Imager (GMI), Jason-2, Jason-3 and Global Navigation Satellite Systems (GNSS) derived WTC at coastal stations. GNSS-derived path Delay Plus (GPD+) corrections have been derived for S3A. Results indicate good overall performance of S3A MWR and GPD+ WTC improvements over MWR-derived WTC, particularly in coastal and polar regions. Based on the outcomes of this study we provide recommendations for improving SAR mode altimeter processing and priorities for future research. @en

The YEASTRACT (http://www.yeastract.com) information system is a tool for the analysis and prediction of transcription regulatory associations in Saccharomyces cerevisiae. Last updated in June 2013, this database contains over 200 000 regulatory associations between transcription factors (TFs) and target genes, including 326 DNA binding sites for 113 TFs. All regulatory associations stored in YEASTRACT were revisited and new information was added on the experimental conditions in which those associations take place and on whether the TF is acting on its target genes as activator or repressor. Based on this information, new queries were developed allowing the selection of specific environmental conditions, experimental evidence or positive/negative regulatory effect. This release further offers tools to rank the TFs controlling a gene or genome-wide response by their relative importance, based on (i) the percentage of target genes in the data set; (ii) the enrichment of the TF regulon in the data set when compared with the genome; or (iii) the score computed using the TFRank system, which selects and prioritizes the relevant TFs by walking through the yeast regulatory network. We expect that with the new data and services made available, the system will continue to be instrumental for yeast biologists and systems biology researchers.@en