This Editorial Note accompanies the special issue devoted to the development of new concepts, theories and methods that address reliability and resilience related to the planning, dynamic operation, and level of service of novel mobility systems. This special issue on ‘Reliability and Resilience of Emerging Mobility Systems’ consists of seven papers which are dedicated to methodological and theoretical developments as well as advanced applications in this domain. Several of the contributions originated from works presented at INSTR2021 (the 8th International Symposium on Transport Network Reliability). In this Editorial note we reflect on the contributions made in each of the articles included in this special issue.