Unitized curtain walls are glazing facade systems widely used in modern architecture for mid and high rise buildings, due to their benefits in terms of lightness, quality control, ease of construction and quick installation. However, recent earthquake surveys have shown damages to these non-structural elements. Slight-to-moderate damage can cause loss of facade functionality, moderate-to-major damage can provoke severe post-earthquake economic losses and pose a life-threatening danger to both building occupants and pedestrians. Despite recent studies on the seismic behavior of unitized curtain walls, research in this field is still limited and experimental investigations typically neglect the study of the overall facade performance as well as the identification of the full sequence of damage states and the ultimate resistance of the facade components. This paper presents the extensive experimental campaign carried out at the laboratory of Permasteelisa Group, in Vittorio Veneto (Italy), to investigate the seismic behaviour of full-scale unitized curtain walls from a holistic and multi-performance perspective. The research aims at providing information about the serviceability performance and the ultimate limit state of alternative facade designs. The tests involve various facade configurations consisting of dry (gasket) vs. wet (structural silicone) glazing systems with different construction details for glass, frame and joints (dimensions and type). The testing sequence consists of displacement-control dynamic cyclic loading and/or time histories at increasingly seismic intensity levels, accounting for in-plane, out-of-plane and vertical movements. Air infiltration tests, water leakage tests and wind resistance tests are performed before and after the low-intensity seismic tests to study the post-earthquake facade serviceability. This paper discusses the research objectives, the specimen details and the test setup, and provides preliminary experimental results.@en