Dental implants became very popular in daily dentistry practice especially in recent decade. However, a long period of osseointegration is the most undesired disadvantage of this method. Several studies have been published related to shorten the osseointegration time. Atmospheric Cold Plasma (ACP) treatment is applied to titanium implants for shortening the osseointegration time by increasing the surface hydrophilicty and cell adhesion rate. In this study, ACP was applied to the surface of the titanium disc to increase hydrophilicty and osteoblast cell adhesion. Contact angle measurements were performed before and after ACP application. The effects of ACP applicaion on osteoblast cells action were evaluated by immunohistochemistry and SEM analysis. The contact angle measurments were decreased after the ACP application significantly. ACP treatment increased the adhesion and proliferation on titanium disc surface without causing oxidative stress on osteoblastic cells. @en