Genome-wide Off-target Cleavage Prediction of CRISPR/Cas Nucleases

Bachelor thesis (2020)

Authors

S.F. de Jong Applied Sciences

Contributors

M. Klein BN/Chirlmin Joo Lab - AS (mentor)
S.M. Depken BN/Martin Depken Lab - AS (mentor)
T. Idema BN/Timon Idema Lab - AS (graduation committee member)
Faculty
Applied Sciences, Applied Sciences
Copyright: © 2020 Sonny Floyd de Jong
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Published Date

03-02-2020

Language

English

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Faculty

Applied Sciences

Abstract

Predicting off-target cleavage sites for CRISPR/Cas nucleases on the human genome based on biophysical modelling and high-throughput biochemical profiling.