Extracellular vesicle quantification and characterization

Common methods and emerging approaches

Review (2019)

Authors

Thomas A. Hartjes Erasmus Medical Centre
Serhii Mytnyk ChemE/Product and Process Engineering - AS
S. Mytnyk ChemE/Product and Process Engineering - AS
Guido W. Jenster Erasmus Medical Centre
G. Jenster Erasmus Medical Centre
Volkert Van Steijn ChemE/Product and Process Engineering - AS
V. van Steijn ChemE/Product and Process Engineering - AS
Volkert van Steijn ChemE/Product and Process Engineering - AS
V. Van Steijn ChemE/Product and Process Engineering - AS
M.E. van Royen Erasmus Medical Centre
Martin E. van Royen Erasmus Medical Centre
Research Group
Education and Student Affairs
Copyright: © 2019 Thomas A. Hartjes, S. Mytnyk, G. Jenster, V. van Steijn, M.E. van Royen
DOI: https://doi.org/10.3390/bioengineering6010007
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Published Date

2019

Language

English

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Research Group

Education and Student Affairs

Abstract

Extracellular vesicles (EVs) are a family of small membrane vesicles that carry information about cells by which they are secreted. Growing interest in the role of EVs in intercellular communication, but also in using their diagnostic, prognostic and therapeutic potential in (bio) medical applications, demands for accurate assessment of their biochemical and physical properties. In this review, we provide an overview of available technologies for EV analysis by describing their working principles, assessing their utility in EV research and summarising their potential and limitations. To emphasise the innovations in EV analysis, we also highlight the unique possibilities of emerging technologies with high potential for further development.

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